Estudios y Papers Low Carb

La alimentación baja en carbohidratos ha estado ganando mucha visibilidad últimamente gracias a diversos estudios y análisis científicos al respecto, que le otorgan una serie de beneficios y superioridad frente a tratamientos convencionales en una diversidad de patologías. Lamentablemente esto no es suficiente y no es extraño encontrarse con profesionales de la salud que aún siguen adheridos a los paradigmas clásicos y lanzan críticas sin fundamento contra cualquier variante Low Carb. Una de las más comunes dice relación con atribuir a este estilo de vida una carencia absoluta de respaldo científico. Esto no sólo demuestra que no son profesionales actualizados en los últimos avances científicos, sino además que tienen sesgos en favor de procedimientos que los nublan frente al cambio de paradigmas.

El objetivo de este post es crear una recopilación (que estará en constante actualización) sobre los últimos avances científicos y publicaciones sobre los beneficios de la alimentación Low Carb en cualquiera de sus variantes.

Resoluciones y declaraciones de instituciones

– Asociación de Diabetes Americana reconoce validez de Low Carb como tratamiento para obesidad y enfermedades metabólicas 

– Asociación de Diabetes Americana y Asociación Europea de Diabetes incorporan a sus pautas de tratamientos la alternativa de Low Carb para tratar obesidad y enfermedades metabólicas

– Very‐low‐calorie ketogenic diet (VLCKD) in the management of metabolic diseases: systematic review and consensus statement from the Italian Society of Endocrinology (SIE)

– Consenso de Walter Willet (Harvard) y otros autores sobre los cuestionamientos a la hipótesis lipídica y los efectos cardiometabólicos del colesterol dietario

– Revisión detallada de más de 70 indicadores con estudios y referencias para cada uno. Ketogenic Diet: A review of the evidence on efficacy and safety

Estudios comparativos de dietas altas y bajas en carbohidratos

– Effects of Low-Carbohydrate and Low-Fat Diets: A Randomized Trial

– Effects of varying amounts of carbohydrate on metabolism after weight loss

– Sugar rush or sugar crash? A meta-analysis of carbohydrate effects on mood

– Metabolic Effects of the Very-Low Carbohydrate Diets: Misunderstood “Villains” of Human Metabolism

– Effects of a Personalized VLCKD on Body Composition and Resting Energy Expenditure in the Reversal of Diabetes to Prevent Complications

– Long-term effects of a ketogenic diet in obese patients

– Greater Weight Loss and Hormonal Changes After 6 Months Diet With Carbohydrates Eaten Mostly at Dinner

– A carbohydrate-reduced high-protein diet improves HbA1c and liver fat content in weight stable participants with type 2 diabetes: a randomised controlled trial.

– A 4-Week Preoperative Ketogenic Micronutrient-Enriched Diet Is Effective in Reducing Body Weight, Left Hepatic Lobe Volume, and Micronutrient Deficiencies in Patients Undergoing Bariatric Surgery: a Prospective Pilot Study.

Diabetes

– Diabetes: Have We Got It All Wrong? 

– A Comprehensive List of Low Carb Research (Compendio de 76 estudios, casi 7 mil personas y 6 estudios con más de 2 años)

– Interest in the Ketogenic Diet Grows for Weight Loss and Type 2 Diabetes

– Management of Type 1 Diabetes With a Very Low–Carbohydrate Diet

– Associations of statin use with glycaemic traits and incident type 2 diabetes

– A clinician’s guide to inpatient low carbohydrate diets for remission of type 2 diabetes : toward a standard of care protocol

– Long-Term Effects of a Novel Continuous Remote Care Intervention Including Nutritional Ketosis for the Management of Type 2 Diabetes: A 2-year Non-randomized Clinical Trial.

– Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study

– Reversing Type 2 Diabetes: A Narrative Review of the Evidence

– Guía para médicos: A clinician’s guide to inpatient low carbohydrate diets for remission of type 2 diabetes : toward a standard of care protocol

– Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies

– Low versus high carbohydrate diet in type 1 diabetes: A 12‐week randomized open‐label crossover study

– Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis

Cerebro

– Ketones supresión brain glucose consumption

– Tau and mTOR: The Hotspots for Multifarious Diseases in Alzheimer’s Development

– Ketone Bodies as a Therapeutic for Alzheimer’s Disease

– Therapeutic Potential of Exogenous Ketone Supplement Induced Ketosis in the Treatment of Psychiatric Disorders: Review of Current Literature

– Dietary sugars, not lipids, drive hypothalamic inflammation

– (PDF) Insulin Signaling Impairment in the Brain as a Risk Factor in Alzheimer’s Disease

Deporte

– A Low-Carbohydrate Ketogenic Diet Reduces Body Mass Without Compromising Performance in Powerlifting and Olympic Weightlifting Athletes

– Deportistas de resistencia siguiendo una dieta cetogénica y aquellos comiendo carbohidratos mantienen las mismas reservas de glucógeno

Naturaleza y Sociedad

– Plant-animal subsistence ratios and macronutrient energy estimations in worldwide hunter-gatherer diets.

– Recent origin and evolution of obesity-income correlation across the United States

– Emerging land use practices rapidly increase soil organic matter

– Sugar industry sour on WHO report

– Metabolic Syndrome and the burden on health care: financial corruption and lifestyle solutions

– Guts and Grease: The Diet of Native Americans – The Weston A. Price Foundation

– How carnivorous are we? The implication for protein consumption

– There was no relationship betand poverty — until high-fructose corn syrupween obesity

Colesterol

– Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease.

– The «cholesterol paradox» among inpatients – retrospective analysis of medical documentation.

– The 2015 US Dietary Guidelines – Ending the 35% Limit on Total Dietary Fat

– Dietary fat: From foe to friend?

– Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73)

– Fats & fatty acids in Indian diets: Time for serious introspection

Impact of Whole Egg Intake on Blood Pressure, Lipids and Lipoproteins in Middle-Aged and Older Population: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

– Statins Stimulate Atherosclerosis and Heart Failure: Pharmacological Mechanisms

– Carbohydrate composition of circulating multiple-modified low-density lipoprotein

– Cholesterol medication could invite diabetes, study suggests

– T2D, Cholesterol, and Neuropathy: What’s the Link?
Lower LDL cholesterol might be a risk factor for nerve damage in type 2 diabetes

Varios

– New research: keto improves liver health markers

– A 4 week preoperative Ketogenic micronutrient-enriched diet si effective in reducing body weight, left hepatic lobe volume, and micronutrient deficiencies in patients undergoing bariatric surgery: a prospective pilot study

– Lysosomal Acid Lipase as a Molecular Target of the Very Low Carbohydrate Ketogenic Diet in Morbidly Obese Patients: The Potential Effects on Liver Steatosis and Cardiovascular Risk Factors.

– Does Protein Harm the Kidneys?

– Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis

– Virta’s impact on NAFLD, the $100B problem affecting 60% of people with T2D

Diego Navarro